Prophylactic vitamin K for the prevention of vitamin K deficiency bleeding in preterm neonates

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[Prophylactic vitamin K for vitamin K deficiency bleeding of the newborn].

BACKGROUND The administration of vitamin K immediately after birth has shown a significant decrease in the incidence of newborn bleeding, but there is not enough evidence to determine the most appropriate method of administration. The objective of this review is to determine the effectiveness of orally administered vitamin K compared to the intramuscular route in the prevention of hemorrhagic d...

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Oral mixed micellar vitamin K for prevention of late vitamin K deficiency bleeding.

OBJECTIVE To determine whether the use of mixed micellar vitamin K improves the efficacy of the 3 x 2 mg oral vitamin K prophylaxis schedule. DESIGN Nationwide active surveillance for vitamin K deficiency bleeding (VKDB) complemented with two surveys on the use of the mixed micellar preparation in hospitals and by paediatricians. SETTING AND PATIENTS Infants in Germany in 1997-2000. INTER...

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Effect of Heat Application during Intramuscular Injection of Vitamin K in Pain Prevention in Neonates

Background: Several modalities have been proposed to reduce procedural pain in neonates. This study was conducted to determine whether heat of a non-human source might help with pain management in infants.Methods: In this clinical trial, 40 full-term healthy neonates in their first hours of life were randomly divided into two groups of intervention and control. The control group was put under a...

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Prophylactic Dosing of Vitamin K to Prevent Bleeding.

BACKGROUND AND OBJECTIVES Based on a high incidence of Vitamin K deficiency bleeding (VKDB) in breastfed infants with thus far unrecognized cholestasis, such as biliary atresia (BA), the Dutch regimen to prevent VKDB in breastfed infants was changed from a daily oral dosage of 25 µg to 150 µg vitamin K. Infants continued to receive 1 mg of vitamin K orally at birth. We compared the efficacy of ...

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Late Vitamin K Deficiency Bleeding in Infants Whose Parents Declined Vitamin K Prophylaxis — Tennessee, 2013

Vitamin K deficiency bleeding (VKDB) is a coagulopathy that develops in infants who do not have sufficient vitamin K stores to support production of clotting factors. In adults, vitamin K is absorbed from food and from vitamin K synthesized by gut bacteria. However, placental transfer in humans is limited; cord blood and infant liver reserve levels of vitamin K are substantially below adult lev...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2018

ISSN: 1465-1858

DOI: 10.1002/14651858.cd008342.pub2